Monroe Carell Jr. Children's Hospital at Vanderbilt
Monroe Carell Jr. Children's Hospital at Vanderbilt
Monroe Carell Jr. Children's Hospital at Vanderbilt
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Monroe Carell Jr.
Children's Hospital
at Vanderbilt
2200 Children's Way
Nashville, TN 37232


(615) 936-1000

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Histiocytosis Program

 

The Histiocytosis Program at Children’s Hospital and Vanderbilt University Medical Center offers comprehensive diagnostic, consultative and therapeutic services for children and adults with Langerhans cell histiocytosis (LCH; also known as eosinophilic granuloma or histiocytosis X), hemophagocytic lymphohistiocytosis (HLH), Rosai-Dorfman disease (RDD; also known as sinus histiocytosis with massive lymphadenopathy), juvenile xanthogranuloma (JXG), and other less common histiocytic disorders.

Histiocytosis is a rare blood disease affecting 1 in 200,000 children born each year in the United States. It is caused by an excess of white blood cells called histiocytes, which cluster together and can attack the skin, bones, lung, liver, spleen, gums, ears, eyes, and the central nervous system. The disease can range from limited involvement that spontaneously goes into remission without treatment to progressive multi-organ involvement that can be chronic and debilitating. In some cases, the disease can be life-threatening.

In some ways, histiocytosis is similar to cancer. It has historically been treated by oncologists with chemotherapy and radiation. The vast majority of people diagnosed with histiocytosis are children under age 10, but it is also found in adults of all ages.

Services provided

Children's Hospital provides consultations for patients with newly diagnosed or recurrent histiocytosis. We also offer individualized treatment plans for patients with newly diagnosed or recurrent histiocytosis.

The Vanderbilt Histiocytosis program participates in international clinical trials conducted by the Histiocyte Society. Please contact us at (615) 936-1762 for more information about open clinical trials here at Vanderbilt.

Our team

For more information about the various forms of histiocytosis, please visit the website of the Histiocytosis Association.

To make an appointment or request more information, please call us at (615) 936-1762.


Last Edited: September 29, 2016
Valued Participant of Vanderbilt Health Affiliated Network